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Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization.

Serine/arginine protein kinases (SRPKs) phosphorylate Arg/Ser dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular processes. The existence of a large internal spacer sequence that separates the bipartite kinase catalytic core is a unique structural feature of...

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Hlavní autoři: Maria Koutroumani, Georgios E Papadopoulos, Metaxia Vlassi, Eleni Nikolakaki, Thomas Giannakouros
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2017-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC5293202?pdf=render
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