Human Tissue Angiotensin Converting Enzyme (ACE) Activity Is Regulated by Genetic Polymorphisms, Posttranslational Modifications, Endogenous Inhibitors and Secretion in the Serum, Lungs and Heart

<b>Objective:</b> Inhibitors of the angiotensin converting enzyme (ACE) are the primarily chosen drugs to treat heart failure and hypertension. Moreover, an imbalance in tissue ACE/ACE2 activity is implicated in COVID-19. In the present study, we tested the relationships between circulating and tiss...

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Автори:	Viktor Bánhegyi, Attila Enyedi, Gábor Áron Fülöp, Attila Oláh, Ivetta Mányiné Siket, Csongor Váradi, Klaudia Bottyán, Mária Lódi, Alexandra Csongrádi, Azeem J. Umar, Miklós Fagyas, Dániel Czuriga, István Édes, Miklós Pólos, Béla Merkely, Zoltán Csanádi, Zoltán Papp, Gábor Szabó, Tamás Radovits, István Takács, Attila Tóth
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2021-07-01
Серія:	Cells
Предмети:	angiotensin converting enzyme ACE cardiovascular disease lung heart tissue-localized
Онлайн доступ:	https://www.mdpi.com/2073-4409/10/7/1708
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