Single-cell and spatial transcriptomic analyses revealing tumor microenvironment remodeling after neoadjuvant chemoimmunotherapy in non-small cell lung cancer

Abstract Non-small cell lung cancer (NSCLC) represents the most common pathological type of lung cancer, and the combination of neoadjuvant immunotherapy with chemotherapy has emerged as the first-line treatment for NSCLC. Nevertheless, the efficacy of this therapeutic approach remains variable. The...

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Detalhes bibliográficos

Principais autores:	Xiaolu Cui, Siyuan Liu, He Song, Jingjing Xu, Yanbin Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-04-01
Colecção:	Molecular Cancer
Assuntos:	Non-small cell lung cancer Single-cell RNA sequencing Spatial transcriptome Neoadjuvant chemoimmunotherapy Tertiary lymphoid structures
Acesso em linha:	https://doi.org/10.1186/s12943-025-02287-w
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