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A Novel Fusion Protein System for the Production of Nanobodies and the SARS-CoV-2 Spike RBD in a Bacterial System

Antibodies are key proteins of the immune system, and they are widely used for both research and theragnostic applications. Among them, camelid immunoglobulins (IgG) differ from the canonical human IgG molecules, as their light chains are completely missing; thus, they have only variable domains on...

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Principais autores: Dóra Nagy-Fazekas, Pál Stráner, Péter Ecsédi, Nóra Taricska, Adina Borbély, László Nyitray, András Perczel
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Bioengineering
Fag:
camelid immunoglobulins
nanobody
bacterial expression
well-folded SARS-CoV-2 S protein RBD variants
Online adgang:https://www.mdpi.com/2306-5354/10/3/389
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