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DeepAR: a novel deep learning-based hybrid framework for the interpretable prediction of androgen receptor antagonists

Abstract Drug resistance represents a major obstacle to therapeutic innovations and is a prevalent feature in prostate cancer (PCa). Androgen receptors (ARs) are the hallmark therapeutic target for prostate cancer modulation and AR antagonists have achieved great success. However, rapid emergence of...

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Váldodahkkit: Nalini Schaduangrat, Nuttapat Anuwongcharoen, Phasit Charoenkwan, Watshara Shoombuatong
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2023-05-01
Ráidu:Journal of Cheminformatics
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Liŋkkat:https://doi.org/10.1186/s13321-023-00721-z
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