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Polymeric Nanovectors Incorporated with Ganciclovir and HSV-<i>tk</i> Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy

In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-<i>tk</i>) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the gene (HSV-<i>tk</i>) is first delivere...

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Principais autores: Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching-An Peng
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2021-03-01
Serija:Molecules
Teme:
Online dostop:https://www.mdpi.com/1420-3049/26/6/1759
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