Development of a green Komagataella phaffii cell factory for sustainable production of plant-derived sesquiterpene (–)-α-bisabolol

(–)-α-Bisabolol is a plant-derived sesquiterpene derived from Eremanthus erythropappus, which can be used as a raw material in cosmetics and has anti-inflammatory function. In this study, we designed six mutation sites of the (–)-α-bisabolol synthase BOS using the plmDCA algorithm. Among these, the...

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Autori principali:	Jintao Cheng, Zhongji Pu, Jiali Chen, Dingfeng Chen, Baoxian Li, Zhengshun Wen, Yuanxiang Jin, Yanlai Yao, Kan Shao, Xiaosong Gu, Guiling Yang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	KeAi Communications Co., Ltd. 2025-03-01
Serie:	Synthetic and Systems Biotechnology
Soggetti:	(–)-α-Bisabolol Komagataella phaffii Enzyme engineering Microbial cell factory Metabolic engineering
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405805X2400125X
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