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Development of an analytical method for simultaneous determination of 38 bile acids and its application in studying the mechanism of WuZhi Pian against rifampicin-induced liver injury

Bile acids (BAs) are crucial signaling molecules involved in liver metabolism regulation. The development of quantitative detection methods for BAs is essential for understanding the molecular mechanisms of liver-related diseases. In this study, we optimized an analytical method to quantify 38 BAs i...

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Principais autores: Caiping Zhang, Jingyu Li, Jianan Zheng, Yiming He, Yongxv Chen, Fangli Liu, Zhongqiu Liu, Zhuoru He
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-08-01
Series:Talanta Open
Assuntos:
Bile acids
Quantitation
Method validation
WuZhi Pian
Rifampicin
Liver injury
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2666831926000019
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