CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice

Abstract Background The annual incidence of traumatic brain injury (TBI) in the United States is over 2.5 million, with approximately 3–5 million people living with chronic sequelae. Compared with moderate-severe TBI, the long-term effects of mild TBI (mTBI) are less understood but important to addr...

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Principais autores:	Wai Hang Cheng, Kris M. Martens, Asma Bashir, Honor Cheung, Sophie Stukas, Ebrima Gibbs, Dhananjay R. Namjoshi, Emily B. Button, Anna Wilkinson, Carlos J. Barron, Neil R. Cashman, Peter A. Cripton, Cheryl L. Wellington
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2019-01-01
Serija:	Alzheimer’s Research & Therapy
Teme:	Traumatic brain injury CHIMERA Alzheimer disease mice Post-traumatic stress disorder Spatial memory Neuroinflammation
Online dostop:	http://link.springer.com/article/10.1186/s13195-018-0461-0
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