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Analysis of single-cell RNA sequencing data to examine the gastric inflammation-to-cancer transition and evaluation of the effect of probiotic on precancerous lesions

Gastric cancer (GC) is the fifth most prevalent malignancy globally. However, its heterogeneity and asymptomatic early-stage development hinder timely diagnosis and effective treatment. Here, we employed single-cell RNA sequencing to delineate the transitional features of pit mucous cells (PMCs) dur...

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Hlavní autoři: Minmin Hu, Shiyang Xu, Ruofei Xu, Xiangjie Qi, Xiaofeng Yu, Jinqi Wang, Yige Li, Yangyang Liu, Guiran Xi, Junbao Yu, Mei Shi
Médium: Artigo
Jazyk:Inglês
Vydáno: KeAi Communications Co., Ltd. 2025-09-01
Edice:Engineering Microbiology
Témata:
Gastric cancer
Inflammation-to-cancer transition
Single-cell RNA sequencing
Probiotic
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2667370325000220
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