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Skipped wells and scientific error during fosfomycin agar dilution and broth microdilution lead to inconsistent minimal inhibitory concentrations and may be cause for reevaluating testing methods for Klebsiella pneumoniae

ABSTRACT Despite the first-line recommendation of fosfomycin for uncomplicated urinary tract infections (UTIs), there are pressing barriers for optimizing its use for the treatment of non-Escherichia coli Enterobacterales UTI. There are no approved breakpoints for oral use against other Enterobacter...

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Principais autores: Morgan L. Bixby, Ellora C. Daley, Lindsey B. Collins, Jenna M. Salay, Alexandra L. Bryson, Elizabeth B. Hirsch
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2024-08-01
Serier:Microbiology Spectrum
Fag:
Klebsiella
UTI
fosfomycin
broth microdilution
susceptibility
Online adgang:https://journals.asm.org/doi/10.1128/spectrum.04205-23
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