Combining metaphase cytogenetics with single nucleotide polymorphism arrays can improve the diagnostic yield and identify prognosis more precisely in myelodysplastic syndromes

Background Myelodysplastic syndromes (MDS) encompass a group of heterogeneous haematopoietic stem cell malignancies characterised by ineffective haematopoiesis, cytological aberrations, and a propensity for progression to acute myeloid leukaemia. Diagnosis and disease prognostic stratification are m...

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Hauptverfasser: Yao Qin, Hang Zhang, Lin Feng, Haichen Wei, Yuling Wu, Chaoran Jiang, Zhihong Xu, Huanling Zhu, Ting Liu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2022-12-01
Schriftenreihe:Annals of Medicine
Schlagworte:
Metaphase cytogenetics
single-nucleotide polymorphism arrays
diagnosis
prognosis
myelodysplastic syndromes
Online Zugang:https://www.tandfonline.com/doi/10.1080/07853890.2022.2125173
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