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HLA-B allele frequencies and implications for pharmacogenetics in the Kuwaiti population

Objective: This study explores the frequency of human leukocyte antigen (HLA) genes, particularly HLA-B alleles, within the Kuwaiti population. We aim to identify alleles with known associations to adverse drug reactions (ADRs) based on existing literature. We focus on the HLA-B gene due to its well...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mohammed Dashti, Md Zubbair Malik, Abdullah Al-Matrouk, Saeeda Bhatti, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-10-01
Schriftenreihe:Frontiers in Pharmacology
Schlagworte:
HLA-B alleles
pharmacogenetics
NGS-HLA typing
Kuwaiti population
precision medicine
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1423636/full
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