Protolytic equilibria in homogeneous and heterogeneous systems of ketoconazole and its direct spectrophotometric determination in tablets
The acid-base equilibria of a diprotic, slightly hydrosoluble base ketoconazole were studied in homogeneous and heterogeneous water systems. The determinations were performed at 25ºC at a constant ionic strength of M(NaCl). The acidity constant Ka1 was determined by potentiometric (pKa1 3.20) and sp...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Serbian Chemical Society
2005-01-01
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| Serie: | Journal of the Serbian Chemical Society |
| Soggetti: | |
| Accesso online: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2005/0352-51390501067V.pdf |
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