In vitro Pharmacokinetics/Pharmacodynamics Evaluation of Fosfomycin Combined with Amikacin or Colistin against KPC2-Producing Klebsiella pneumoniae

Objectives: The emergence of carbapenem-resistant Enterobacteriaceae, especially Klebsiella pneumoniae, has become a major concern in clinic settings. Combination therapy is gaining momentum to counter the secondary resistance and potential suboptimal efficacy of monotherapy. The aim of this study w...

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Detalhes bibliográficos

Principais autores:	Wei Yu, Kai Zhou, Lihua Guo, Jinru Ji, Tianshui Niu, Tingting Xiao, Ping Shen, Yonghong Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2017-06-01
coleção:	Frontiers in Cellular and Infection Microbiology
Assuntos:	pharmacokinetics/pharmacodynamics fosfomycin amikacin colistin KPC-producing Klebsiella pneumoniae
Acesso em linha:	http://journal.frontiersin.org/article/10.3389/fcimb.2017.00246/full
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