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Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids

ABSTRACT Plasmid-mediated antimicrobial resistance is one of the major threats to public health worldwide. The mechanisms involved in the plasmid/host coadaptation are still poorly characterized, and their understanding is crucial to comprehend the genesis and evolution of multidrug-resistant bacter...

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Auteurs principaux: Manuel Ares-Arroyo, Miguel Fernández-García, Emilia Wedel, Natalia Montero, Coral Barbas, M. Fernanda Rey-Stolle, Antonia Garcia, Bruno González-Zorn
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2022-12-01
Collection:mSphere
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Accès en ligne:https://journals.asm.org/doi/10.1128/msphere.00184-22
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