Metagenome-assembled genomes from a population-based cohort uncover novel gut species and within-species diversity, revealing prevalent disease associations

ABSTRACT Metagenomic profiling has advanced the understanding of microbe-host interactions. However, widely used read-based approaches are limited by incomplete reference databases and the inability to resolve strain-level variation. Here, we present a scalable, genome-resolved framework that integr...

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Główni autorzy:	Kateryna Pantiukh, Kertu Liis Krigul, Oliver Aasmets, Elin Org
Format:	Artigo
Język:	Inglês
Wydane:	American Society for Microbiology 2026-04-01
Seria:	mSystems
Hasła przedmiotowe:	gut microbiome metagenome-assembled genomes genome unit number population microbiome metagenomics metagenome-wide association study
Dostęp online:	https://journals.asm.org/doi/10.1128/msystems.00114-26
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