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Reactive oxygen species accelerated glycation for oxygen-independent corneal cross-linking

BackgroundThe pentose-initiated Maillard reaction may serve as an oxygen-independent, non-enzymatic crosslinking (CxL) mechanism, but its slow kinetics limit clinical applicability. We hypothesize that glycation-mediated CxL can be accelerated by reactive oxygen species (ROS), potentially enabling i...

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Autori principali: Jiashuai Fan, Sinisa Vukelic
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-03-01
Serie:Frontiers in Bioengineering and Biotechnology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fbioe.2026.1695384/full
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