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From Biology to Clinical Practice: Iron Chelation Therapy With Deferasirox

Iron chelation therapy (ICT) has become a mainstay in heavily transfused hematological patients, with the aim to reduce iron overload (IOL) and prevent organ damage. This therapeutic approach is already widely used in thalassemic patients and in low-risk Myelodysplastic Syndrome (MDS) patients. More...

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Principais autores: Giuseppe A. Palumbo, Sara Galimberti, Wilma Barcellini, Daniela Cilloni, Nicola Di Renzo, Elena Maria Elli, Carlo Finelli, Luca Maurillo, Alessandra Ricco, Pellegrino Musto, Rodolfo Russo, Roberto Latagliata
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-10-01
coleção:Frontiers in Oncology
Assuntos:
iron chelation therapy (ICT)
deferasirox
myelodysplastic syndromes (MDS)
myelofibrosis (MF)
radical oxygen species (ROS)
iron toxicity
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2021.752192/full
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