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Development of patient-derived lymphomoids with preserved tumor architecture for lymphoma therapy screening

Abstract The efficacy of anti-cancer therapies depends on the genomic composition of the tumor, its microenvironment, spatial organization, and intra-tumor heterogeneity. B-cell lymphomas are a heterogeneous group of tumors emerging from B-cells at different stages of differentiation and exhibiting...

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Hlavní autoři: Albert Santamaria-Martínez, Justine Epiney, Divyanshu Srivastava, Daniele Tavernari, Marco Varrone, Dina Milowich, Igor Letovanec, Thorsten Krueger, Rafael Duran, Giovanni Ciriello, Anne Cairoli, Elisa Oricchio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-12-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-024-55098-w
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