Impact of Promoter-Independent CpG-Rich A2UCOE Subregions on Transgene Expression

Aim: This study aimed to evaluate the ability of CpG-rich subregions within the A2UCOE element, excluding the HNRPA2B1 and CBX3 promoters, to sustain long-term transgene expression in lentiviral systems. These regions are cloned upstream of the spleen focus-forming virus (SFFV) promoter and tested i...

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Autores principales:	Ali Osman Arslan, Ömer Faruk Anakök
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Duzce University 2025-12-01
Colección:	Düzce Tıp Fakültesi Dergisi
Materias:	promotor aktivitesi ucoe fonksiyonu trasnkripsiyonel susturma sffv promotörü gen ekspresyonu stabilitesi promoter activity ucoe function transcriptional silencing sffv promoter gene expression stability
Acceso en línea:	https://dergipark.org.tr/en/download/article-file/4670442
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