Integrating single-cell RNA sequencing with spatial transcriptomics reveals immune landscape for interstitial cystitis

Abstract Interstitial cystitis (IC) is a severely debilitating and chronic disorder with unclear etiology and pathophysiology, which makes the diagnosis difficult and treatment challenging. To investigate the role of immunity in IC bladders, we sequenced 135,091 CD45+ immune cells from 15 female pat...

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Detalhes bibliográficos

Principais autores:	Liao Peng, Xi Jin, Bo-ya Li, Xiao Zeng, Bang-hua Liao, Tao Jin, Jia-wei Chen, Xiao-shuai Gao, Wei Wang, Qing He, Guo Chen, Li-Na Gong, Hong Shen, Kun-jie Wang, Hong Li, De-yi Luo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2022-05-01
coleção:	Signal Transduction and Targeted Therapy
Acesso em linha:	https://doi.org/10.1038/s41392-022-00962-8
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