The role of Rif1 in telomere length regulation is separable from its role in origin firing
To examine the established link between DNA replication and telomere length, we tested whether firing of telomeric origins would cause telomere lengthening. We found that RIF1 mutants that block Protein Phosphatase 1 (PP1) binding activated telomeric origins but did not elongate telomeres. In a seco...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications Ltd
2020-06-01
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| Seria: | eLife |
| Hasła przedmiotowe: | |
| Dostęp online: | https://elifesciences.org/articles/58066 |
| Etykiety: |
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