A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

Metastasis is a multistep process in which cells must detach, migrate/invade local structures, intravasate, circulate, extravasate, and colonize. A full understanding of the complexity of this process has been limited by the lack of ability to study these steps in isolation with detailed molecular a...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tyler A. Allen, Mark M. Cullen, Nathan Hawkey, Hiroyuki Mochizuki, Lan Nguyen, Elyse Schechter, Luke Borst, Jeffrey A. Yoder, Jennifer A. Freedman, Steven R. Patierno, Ke Cheng, William C. Eward, Jason A. Somarelli
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-09-01
Schriftenreihe:	Frontiers in Oncology
Schlagworte:	angiopellosis circulating tumor cell cluster tumor cell extravasation cancer exodus hypothesis metastasis osteosarcoma
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fonc.2021.641187/full
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