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Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways

Ischemia-reperfusion (I/R) induced acute kidney injury (AKI) is a significant health problem with high morbidity and mortality, yet prophylaxis strategies and effective drugs are limited. Sanqi oral solution (SQ) is a formulated medicine widely used in clinical settings to treat various renal diseas...

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Principais autores: Ruimin Tian, Pinchao Wang, Lihua Huang, Chuang Li, Zhaoyu Lu, Zhisheng Lu, Aijun Wu, Kun Bao, Wei Mao, Qingming Huang, Peng Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
coleção:Frontiers in Pharmacology
Assuntos:
renal ischemia-reperfusion (I/R)
acute kidney injury (AKI)
Radix Astragali
Radix Notoginseng
apoptosis
autophagy
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2020.537147/full
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