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Pan-cancer atlas of somatic core and linker histone mutations

Abstract Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the prevalence and the clinical and biological implications of histone gene mutations in malignant tumors remain incompletely defined. To address th...

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Autori principali: Erin R. Bonner, Adam Dawood, Heather Gordish-Dressman, Augustine Eze, Surajit Bhattacharya, Sridevi Yadavilli, Sabine Mueller, Sebastian M. Waszak, Javad Nazarian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2023-08-01
Serie:npj Genomic Medicine
Accesso online:https://doi.org/10.1038/s41525-023-00367-8
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