Blockage of retinoic acid signaling via RARγ suppressed the proliferation of pancreatic cancer cells by arresting the cell cycle progression of the G1-S phase

Abstract Background Our study and several studies have reported that in some cancers, including pancreatic ductal adenocarcinoma (PDAC), the expression of squamous lineage markers, such as esophagus-tissue-specific genes, correlated with a poor prognosis. However, the mechanism by which the acquisit...

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Hlavní autoři:	Kohei Yamakawa, Michiyo Koyanagi-Aoi, Akihito Machinaga, Nobuyuki Kakiuchi, Tomonori Hirano, Yuzo Kodama, Takashi Aoi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-05-01
Edice:	Cancer Cell International
Témata:	Pancreatic ductal adenocarcinoma Retinoic acid signaling Retinoic acid receptor γ Cell proliferation Cell cycle
On-line přístup:	https://doi.org/10.1186/s12935-023-02928-4
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