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Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε

<p>Abstract</p> <p>Background</p> <p>Inactivating mutations of SMAD4 are frequent in metastatic colorectal carcinomas. In previous analyses, we were able to show that restoration of Smad4 expression in Smad4-deficient SW480 human colon carcinoma cells was adequate to suppress tumorigenicity and inva...

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Principais autores: Schmiegel Wolff, Klein-Scory Susanne, Marcus Katrin, Schulenborg Thomas, Herbrand Ulrike, Jackstadt René, Munding Johanna B, Maghnouj Abdelouahid, Liffers Sven-T, Schwarte-Waldhoff Irmgard, Meyer Helmut E, Stühler Kai, Hahn Stephan A
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2011-04-01
Serier:BMC Cancer
Online adgang:http://www.biomedcentral.com/1471-2407/11/137
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