Comparison of the therapeutic effects of sacubitril and valsartan combination versus metformin in experimentally induced polycystic ovary syndrome in rats

Objective(s): Our study aimed to demonstrate the therapeutic effects of sacubitril (an inhibitor of neprilysin) and/or valsartan (an ARB) in an experimentally induced polycystic ovary syndrome (PCOS) model and in PCOS-induced insulin resistance.Materials and Methods: After 21 days of letrozole 1 mg/...

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Autors principals:	Muhammed Yayla, Bengul Ozdemir Sarikaya, Erdem Toktay, Huseyin Gul, Ugur Ermis, Damla Binnetoglu
Format:	Artigo
Idioma:	Inglês
Publicat:	Mashhad University of Medical Sciences 2025-12-01
Col·lecció:	Iranian Journal of Basic Medical Sciences
Matèries:	insulin resistance neprilysin and arb pcos rat sacubitril and valsartan
Accés en línia:	https://ijbms.mums.ac.ir/article_26801_9011c7ae733a4426326dee7425a6838f.pdf
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