Phage Henu12-resistant mutant derives fitness trade-offs in Shigella dysenteriae

ABSTRACT The rapid emergence of multidrug-resistant Shigella dysenteriae strains necessitates new therapeutic approaches, such as phage therapy. Phages are considered a promising adjunct to antibiotics. The rapid emergence of phage-resistant bacterial mutants represents a major challenge in clinical...

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Bibliografiske detaljer

Principais autores:	Salwa E. Gomaa, Yuhan Wang, Jingjing Li, Huiru Cao, Jiawen Shen, Xiaotao Dong, Yangyang Liu, Na Chen, Qiming Li, Zhongyi Yan, Yulu Du, Xinying Ji, Jing Zhao, Yinqiong Tu, Tieshan Teng
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology 2025-12-01
Serier:	Microbiology Spectrum
Fag:	Shigella dysenteriae antimicrobial resistance phage synergy phage resistant fitness trade-offs
Online adgang:	https://journals.asm.org/doi/10.1128/spectrum.01150-25
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