Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease

Neurodegenerative diseases such as Alzheimer’s disease (AD) are multifactorial with several different pathologic mechanisms. Therefore, it is assumed that multitargeted-directed ligands (MTDLs) which interact with different biological targets relevant to the diseases, might offer an improved therape...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Donia E. Hafez, Mariam Dubiel, Gabriella La Spada, Marco Catto, David Reiner-Link, Yu-Ting Syu, Mohammad Abdel-Halim, Tsong-Long Hwang, Holger Stark, Ashraf H. Abadi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2023-12-01
Schriftenreihe:	Journal of Enzyme Inhibition and Medicinal Chemistry
Schlagworte:	Multitarget-directed ligands Alzheimer’s disease cholinesterase inhibitors histamine H3 receptor ligands monoamine oxidase inhibitors benzothiazole derivatives
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/14756366.2023.2175821
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