Unveiling radiobiological traits and therapeutic responses of BRAFV600E-mutant colorectal cancer via patient-derived organoids

Abstract Background Radiotherapy (RT) is an essential treatment for colorectal cancer (CRC), yet the factors influencing radiosensitivity remain unclear. In the quest to enhance the therapeutic efficacy in CRC, the interplay between genetic mutations and RT sensitivity has emerged as a pivotal yet e...

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Үндсэн зохиолчид:	Peiyuan Mu, Shaobo Mo, Xingfeng He, Hui Zhang, Tao Lv, Ruone Xu, Luoxi He, Fan Xia, Shujuan Zhou, Yajie Chen, Yaqi Wang, Lijun Shen, Juefeng Wan, Lili Huang, Weiqing Lu, Xinyue Liang, Xiaomeng Li, Ping Lu, Junjie Peng, Guoqiang Hua, Kewen Hu, Zhen Zhang, Yan Wang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-03-01
Цуврал:	Journal of Experimental & Clinical Cancer Research
Нөхцлүүд:	BRAFV600E-mutant Radiotherapy Organoid model Precision treatment Colorectal cancer
Онлайн хандалт:	https://doi.org/10.1186/s13046-025-03349-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!