Acetazolamide and human carbonic anhydrases: retrospect, review and discussion of an intimate relationship
Acetazolamide (AZM) is a strong pharmacological sulphonamide-type (R-SO2-NH2, pKa 7.2) inhibitor of the activity of several carbonic anhydrase (CA) isoforms, notably of renal CA II (Ki, 12 nM) and CA IV (Ki, 74 nM). AZM is clinically used for about eighty years in various diseases including epilepsy...
Gardado en:
| Autor Principal: | |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis Group
2024-12-01
|
| Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Assuntos: | |
| Acceso en liña: | https://www.tandfonline.com/doi/10.1080/14756366.2023.2291336 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|