Tachykinin acts upstream of autocrine Hedgehog signaling during nociceptive sensitization in Drosophila

Pain signaling in vertebrates is modulated by neuropeptides like Substance P (SP). To determine whether such modulation is conserved and potentially uncover novel interactions between nociceptive signaling pathways we examined SP/Tachykinin signaling in a Drosophila model of tissue damage-induced no...

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Autors principals:	Seol Hee Im, Kendra Takle, Juyeon Jo, Daniel T Babcock, Zhiguo Ma, Yang Xiang, Michael J Galko
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2015-11-01
Col·lecció:	eLife
Matèries:	nociceptive sensitization Substance P Hedgehog electrophysiology Trp channels neuropeptide
Accés en línia:	https://elifesciences.org/articles/10735
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