RNA N6-methyladenosine modification mediates downregulation of NR4A1 to facilitate malignancy of cervical cancer

Abstract Background N6-methyladenosine is the most abundant eukaryotic mRNA modification and alters a wide range of cellular processes in cancer. Therefore, defining the molecular details are critical for understanding the regulatory mechanism of m6A modification. Results We found that METTL3, a cor...

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Hlavní autoři:	Tao Yu, Fuxia Wu, Yan Jia, Xue Zhang, Xiaozhen Qi, Zeyuan Jin, Tongxin Hao, Jianing Zhao, Ziyu Liu, Chaokun Wang, Minmin Niu, Qin Yue, Min Li, Yankun Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2022-12-01
Edice:	Cell & Bioscience
Témata:	RNA N6-methyladenosine METTL3 YTHDF2 NR4A1 Cervical cancer AKT1
On-line přístup:	https://doi.org/10.1186/s13578-022-00937-w
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