Antigenic Matching of rHVT-H5 via CRISPR/Cas9 Confers Complete Protection Against Novel H5N1 Clade 2.3.4.4b in Chicken

The widespread panzootic of clade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 necessitates the development of vaccine platforms capable of rapid adaptation to emerging antigenic variants. Although commercial recombinant turkey herpesvirus (rHVT) vaccines are available, they often utilize...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Sang-Won Kim, Jong-Yeol Park, Ji-Eun Son, Cheng-Dong Yu, Ki-Woong Kim, Won-Bin Jeon, Yu-Ri Choi, Hyung-Kwan Jang, Bai Wei, Min Kang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-01-01
Schriftenreihe:	Veterinary Sciences
Schlagworte:	highly pathogenic avian influenza virus clade 2.3.4.4b recombinant viral vector vaccine herpesvirus of turkeys CRISPR/Cas9
Online-Zugang:	https://www.mdpi.com/2306-7381/13/2/127
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