Neutrophil elastase promotes mucin secretion in airway epithelial cells through the MARCKS/ACK1/cortactin pathway

Introduction Excessive mucus secretion in airway epithelial cells is a hallmark of various airway inflammatory diseases. Neutrophil elastase (NE) is a recognized inducer of mucus secretion, yet the precise mechanisms underlying this process remain inadequately understood. This study aims to investig...

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Hauptverfasser:	Mingxin He, Qi Li, SHUYUAN OUYANG, Yan Liu, Juliy M. Perelman, Victor P. Kolosov, Xiangdong Zhou, Yanyan Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Termedia Publishing House 2025-10-01
Schriftenreihe:	Central European Journal of Immunology
Schlagworte:	airway epithelial cells neutrophil elastase mucin 5ac myristoylated alanine-rich c-kinase substrate activated cdc42 kinase 1 cortactin
Online-Zugang:	https://ceji.termedia.pl/Neutrophil-elastase-promotes-mucin-secretion-in-airway-epithelial-cells-through-the,200655,0,2.html
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