Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort

Abstract Ependymoma is the second most common malignant brain tumor in children. The etiology is largely unknown and germline DNA sequencing studies focusing on childhood ependymoma are limited. We therefore performed germline whole-genome sequencing on a population-based cohort of children diagnose...

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Bibliografiska uppgifter

Huvudupphov:	Jon Foss-Skiftesvik, Ulrik Kristoffer Stoltze, Thomas van Overeem Hansen, Lise Barlebo Ahlborn, Erik Sørensen, Sisse Rye Ostrowski, Solvej Margrete Aldringer Kullegaard, Adrian Otamendi Laspiur, Linea Cecilie Melchior, David Scheie, Bjarne Winther Kristensen, Jane Skjøth-Rasmussen, Kjeld Schmiegelow, Karin Wadt, René Mathiasen
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	BMC 2022-08-01
Serie:	Acta Neuropathologica Communications
Ämnen:	DNA methylation profiling Molecular classification Genomics Genetic susceptibility Pediatrics
Länkar:	https://doi.org/10.1186/s40478-022-01429-1
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