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Impaired cecal motility and secretion alongside expansion of gut-associated lymphoid tissue in the Nlgn3 R451C mouse model of autism

Abstract Individuals with Autism Spectrum Disorder (ASD; autism) commonly present with gastrointestinal (GI) illness in addition to core diagnostic behavioural traits. The appendix, or cecum in mice, is important for GI homeostasis via its function as a key site for fermentation and a microbial rese...

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Bibliografiske detaljer
Principais autores: Chalystha Yie Qin Lee, Gayathri K. Balasuriya, Madushani Herath, Ashley E. Franks, Elisa L. Hill-Yardin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2023-08-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-023-39555-y
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