Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation

Despite the efficacy and potential therapeutic benefits that poly(lactic-co-glycolic acid) (PLGA) nanomedicine formulations can offer, challenges related to large-scale processing hamper their clinical and commercial development. Major hurdles for the launch of a polymeric nanocarrier product on the...

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Autori principali:	Maria Camilla Operti, Alexander Bernhardt, Vladimir Sincari, Eliezer Jager, Silko Grimm, Andrea Engel, Martin Hruby, Carl Gustav Figdor, Oya Tagit
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-01-01
Serie:	Pharmaceutics
Soggetti:	PLGA poly(lactic-co-glycolic acid) nanomedicine nanoparticles scale-up manufacturing clinical translation
Accesso online:	https://www.mdpi.com/1999-4923/14/2/276
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