Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency.

Sirtuins are NAD+ dependent deacetylases, which regulate mitochondrial energy metabolism as well as cellular response to stress. The NAD/NADH-system plays a crucial role in oxidative phosphorylation linking sirtuins and the mitochondrial respiratory chain. Furthermore, sirtuins are able to directly...

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Autors principals:	Arne Björn Potthast, Theresa Heuer, Simone Johanna Warneke, Anibh Martin Das
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2017-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5653369?pdf=render
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