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Role of Melatonin in Ameliorating the Harmful Effects of Tramadol on the Frontal Cortex of Adult Male Albino Rat (Histological and Immunohistochemical Study)

Introduction: Tramadol is the foremost utilized opioid in moderate to severe pain. Previous studies reported changes in the rat’s brain after either oral or intraperitoneal tramadol administration. Melatonin ‘neurohormone’ has antioxidant and anti-apoptotic effects on the brain.Aim of the Work: This...

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Autor principal: Enas Anwar Bekheet
Format: Artigo
Idioma:Inglês
Publicat: Egyptian Society of Histology and Cytology 2024-06-01
Col·lecció:The Egyptian Journal of Histology
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Accés en línia:https://ejh.journals.ekb.eg/article_300615_afc6e99bb92f7bccbdf9a89dc8532d23.pdf
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