Selenoprotein GPX3 regulates NADPH oxidase expression by inhibiting the MAPK signaling pathway and thereby attenuating the inflammatory response in renal ischemia-reperfusion injury

Renal ischemia-reperfusion injury (IRI) is one of the major causes of acute kidney injury, and the inflammatory response is considered a key factor. The selenoprotein GPX3, a member of the glutathione peroxidase family, has gradually attracted attention for its anti-inflammatory properties. However,...

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Principais autores:	Jun Pei, Jie Zhang, Chengjun Yu, Jin Luo, Sheng Wen, Yi Hua, Guanghui Wei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2026-03-01
Colecção:	Genes and Diseases
Assuntos:	GPX3 Inflammation Ischemia-reperfusion injury Kidney Selenoprotein
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352304225001291
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