Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity

Abstract Polymers can facilitate detergent-free extraction of membrane proteins into nanodiscs (e.g., SMALPs, DIBMALPs), incorporating both integral membrane proteins as well as co-extracted native membrane lipids. Lipid-only SMALPs and DIBMALPs have been shown to possess a unique property; the abil...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Henry Sawczyc, Takashi Tatsuta, Carl Öster, Spyridon Kosteletos, Sascha Lange, Claudia Bohg, Thomas Langer, Adam Lange
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-08-01
Schriftenreihe:	Nature Communications
Online-Zugang:	https://doi.org/10.1038/s41467-024-51989-0
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!