Two parallel medial prefrontal cortex-amygdala pathways mediate memory deficits via glutamatergic projection in surgery mice

Summary: The neural circuit mechanisms underlying postoperative cognitive dysfunction (POCD) remain elusive. We hypothesized that projections from the medial prefrontal cortex (mPFC) to the amygdala are involved in POCD. A mouse model of POCD in which isoflurane (1.5%) combined with laparotomy was u...

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Detalhes bibliográficos

Principais autores:	Xiao-Yu Sun, Le Liu, Yu-Tong Song, Tong Wu, Teng Zheng, Jing-Ru Hao, Jun-Li Cao, Can Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-07-01
Colecção:	Cell Reports
Assuntos:	CP: Neuroscience
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124723007301
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