Exploring the Impact of PARK2 Mutations on the Total and Mitochondrial Proteome of Human Skin Fibroblasts

Mutations in PARK2 gene are the most frequent cause of familial forms of Parkinson’s disease (PD). This gene encodes Parkin, an E3 ubiquitin ligase involved in several cellular mechanisms, including mitophagy. Parkin loss-of-function is responsible for the cellular accumulation of damaged mitochondr...

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Xehetasun bibliografikoak

Egile Nagusiak:	Mara Zilocchi, Ilaria Colugnat, Marta Lualdi, Monica Meduri, Federica Marini, Victor Corasolla Carregari, Mohamed Taha Moutaoufik, Sadhna Phanse, Luisa Pieroni, Mohan Babu, Barbara Garavaglia, Mauro Fasano, Tiziana Alberio
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2020-06-01
Saila:	Frontiers in Cell and Developmental Biology
Gaiak:	proteomic alterations interactome mitophagy mitochondria Parkinson’s Disease Parkin (PARK2)
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fcell.2020.00423/full
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!