Mass Spectrometric Detection of Formaldehyde-Crosslinked PBMC Proteins in Cell-Free DNA Blood Collection Tubes

Streck tubes are commonly used to collect blood samples to preserve cell-free circulating DNA. They contain imidazolidinyl urea as a formaldehyde-releasing agent to stabilize cells. We investigated whether the released formaldehyde leads to crosslinking of intracellular proteins. Therefore, we emplo...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Daniel Röth, Jessica Molina-Franky, John C. Williams, Markus Kalkum
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2023-11-01
Sarja:	Molecules
Aiheet:	formaldehyde Streck tubes peripheral blood mononuclear cells crosslinking targeted mass spectrometry
Linkit:	https://www.mdpi.com/1420-3049/28/23/7880
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