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Anti-Obesity Effect of Chlorin e6-Mediated Photodynamic Therapy on Mice with High-Fat-Diet-Induced Obesity

This study aimed to evaluate the efficacy of Chlorin e6 (Ce6)-based photodynamic therapy (PDT) for anti-obesity activities in high-fat-diet (HFD)-induced obesity mouse models. We induced obesity in C57BL/6 mice by HFD and administered Ce6 (2.5 or 5 mg/kg) orally with 3 h of incubation. The mice were...

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Main Authors: Rajeev Shrestha, Pallavi Gurung, Junmo Lim, Til Bahadur Thapa Magar, Cheong-Wun Kim, Hak Yong Lee, Yong-Wan Kim
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
obesity
chlorin e6
photodynamic therapy
leptin
adiponectin
Online Access:https://www.mdpi.com/1424-8247/16/7/1053
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