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DEVELOPMENT AND CHARACTERIZATION OF PROTRANSFERSOMES LOADED WITH MODEL DRUG FOR TRANSDERMAL DELIVERY

Repaglinide (REP) is an oral synthetic antidiabetic that is administered to enhance meal-induced insulin production. It is quickly excreted from the body through the biliary system. Due its first-pass metabolism that occurs in the liver, REP has a low oral bioavailability of 56%. Its half-life in sy...

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Autores principales: Hatem Tawfek, Mohamed Nasr-Eldin, Mohamed Akl, Mohamed El-sayed, Ahmed Gardouh
Formato: Artigo
Lenguaje:Inglês
Publicado: Al-Azhar University, Faculty of Pharmacy 2024-09-01
Colección:Al-Azhar Journal of Pharmaceutical Sciences
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Acceso en línea:https://ajps.journals.ekb.eg/article_429434_7ee655b0e67a58cfc6d807ed3ef0dd23.pdf
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