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Testing the differential adhesion hypothesis across the epithelial−mesenchymal transition

We analyze the mechanical properties of three epithelial/mesenchymal cell lines (MCF-10A, MDA-MB-231, MDA-MB-436) that exhibit a shift in E-, N- and P-cadherin levels characteristic of an epithelial−mesenchymal transition associated with processes such as metastasis, to quantify the role of cell coh...

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Autori principali: Steve Pawlizak, Anatol W Fritsch, Steffen Grosser, Dave Ahrens, Tobias Thalheim, Stefanie Riedel, Tobias R Kießling, Linda Oswald, Mareike Zink, M Lisa Manning, Josef A Käs
Natura: Artigo
Lingua:Inglês
Pubblicazione: IOP Publishing 2015-01-01
Serie:New Journal of Physics
Soggetti:
compartmentalization
differential adhesion
cell–cell adhesion
cell segregation and sorting
droplet culture
cadherins
Accesso online:https://doi.org/10.1088/1367-2630/17/8/083049
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